Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201726 | 0.85 | NPC1 (0.37) | KDM4EHPGDALDH1A1TUBB4ATUBB | |
| SCHEMBL29929274 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL4070144 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL1498432 | 0.80 | KDM4E (0.46) | KDM4EHPGDALDH1A1CA12CA1 | |
| SCHEMBL1202813 | 0.79 | MAPT (0.34) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2098039 | 0.79 | KDM4E (0.45) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL5264347 | 0.77 | TUBB4A (0.45) | KDM4EALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL1201584 | 0.76 | — | — | |
| SCHEMBL31674128 | 0.76 | SYK (0.43) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL30959064 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488824-B2 | Process for the production of substituted nicotinic acid esters | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-10 | — | — | US | disclosed |
| EP-1601653-B1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED NICOTINIC ACID ESTERS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-02-04 | — | — | EP | disclosed |
| US-20060199964-A1 | Process for the production of substituted nicotinic acid esters | SYNGENTA CROP PROTECTION, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-1601653-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED NICOTINIC ACID ESTERS | Syngenta Participations AG (CH) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004078729-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED NICOTINIC ACID ESTERS | SYNGENTA PARTICIPATIONS AG (CH) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199964-A1 | Process for the production of substituted nicotinic acid esters | CHRM1, CHRM5, CHRNA5 | KDM4E 3555/4885HPGD 202/4885ALDH1A1 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.