SCHEMBL29929274

SCHEMBL29929274

CCOC(=O)c1ccc(C(F)(F)F)nc1COCCOC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.40
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TSHR P16473 2/20 0.38
NPSR1 Q6W5P4 1/20 0.37
FOS P01100 1/20 0.36
JUN P05412 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4070144 1.00 KDM4E (0.40) KDM4ECA12CA1CA2CA7
SCHEMBL18869269 0.89 TUBB4A (0.46) NPC1RAB9ATUBB4ATUBBTUBA3C
SCHEMBL29929108 0.85 NPC1 (0.40) NPC1RAB9ATUBB4ATUBBTUBA3C
SCHEMBL1201731 0.85 NPC1 (0.40) NPC1RAB9ATUBB4ATUBBTUBA3C
SCHEMBL18487179 0.84 NPC1 (0.37) NPC1RAB9ATUBB4ATUBBTUBA3C
SCHEMBL31330735 0.84 PDE4B (0.38) NPC1RAB9ATUBB4ATUBBTUBA3C
SCHEMBL3276376 0.84 PDE4B (0.38) NPC1RAB9ATUBB4ATUBBTUBA3C
SCHEMBL18323055 0.84 MEN1 (0.42) KDM4ECA12CA1CA2CA7
SCHEMBL1498432 0.81 KDM4E (0.46) KDM4ECA12CA1CA2CA7
SCHEMBL4070142 0.80 KDM4E (0.40) KDM4ECA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232008-A Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate 山东潍坊润丰化工股份有限公司 2022-10-25 CN disclosed