Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073451 | 0.90 | TLR8 (0.31) | TLR8TLR7 | |
| SCHEMBL4070545 | 0.73 | TLR8 (0.34) | TLR8TLR7 | |
| SCHEMBL5805491 | 0.72 | DCPS (0.38) | TLR8TLR7 | |
| SCHEMBL5271662 | 0.70 | TLR8 (0.43) | TLR8 | |
| SCHEMBL18268482 | 0.70 | TLR7 (0.41) | PDE4DTLR8TLR7 | |
| SCHEMBL3862404 | 0.64 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL18587589 | 0.64 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL18588106 | 0.63 | TLR8 (0.42) | TLR8TLR7 | |
| SCHEMBL9036182 | 0.63 | TLR7 (0.52) | TLR8TLR7 | |
| SCHEMBL4586839 | 0.63 | TLR7 (0.38) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673087-A4 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1673087-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005032484-A9 | Alkoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-05-18 | — | — | WO | disclosed |
| WO-2005032484-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |