Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070285 | 0.90 | PDE4A (0.32) | TLR8TLR7 | |
| SCHEMBL4070545 | 0.83 | TLR8 (0.34) | TLR8TLR7 | |
| SCHEMBL5805491 | 0.81 | DCPS (0.38) | TLR8TLR7 | |
| SCHEMBL17181527 | 0.76 | TLR8 (0.37) | TLR8TLR7NUDT1 | |
| SCHEMBL4068953 | 0.75 | MTNR1A (0.33) | TLR8TLR7 | |
| SCHEMBL4064967 | 0.75 | TLR7 (0.34) | TLR8TLR7 | |
| SCHEMBL5805143 | 0.74 | TLR7 (0.42) | TLR8TLR7 | |
| SCHEMBL18588106 | 0.73 | TLR8 (0.42) | TLR8TLR7NUDT1 | |
| SCHEMBL4763415 | 0.72 | TLR7 (0.49) | TLR8TLR7NUDT1 | |
| SCHEMBL4654594 | 0.72 | TLR7 (0.39) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673087-A4 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1673087-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005032484-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |