Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464267 | 0.91 | CNR2 (0.51) | CNR1CNR2ALDH1A1KMT2ALMNA | |
| SCHEMBL4072111 | 0.88 | ALDH1A1 (0.44) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL1464427 | 0.87 | ABCC9 (0.48) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL1464819 | 0.78 | CNR2 (0.53) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL1464451 | 0.78 | CNR2 (0.55) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL12635982 | 0.77 | CNR2 (0.47) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL1464391 | 0.77 | CNR2 (0.55) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL1464240 | 0.77 | CNR2 (0.48) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL12635976 | 0.77 | CNR2 (0.49) | CNR1CNR2ABCC9ABCC8KCNJ11 | |
| SCHEMBL4164059 | 0.74 | CNR2 (0.44) | CNR1CNR2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |