Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 3/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419374 | 0.76 | ALDH1A1 (0.39) | WDR5MEN1ALDH1A1KMT2AALPL | |
| SCHEMBL407940 | 0.75 | PNLIP (0.39) | MEN1ALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL30975319 | 0.74 | SLC6A4 (0.34) | KDM1AALDH1A1MAOAMAOBALPL | |
| SCHEMBL1316543 | 0.72 | MARS1 (0.37) | — | |
| SCHEMBL4704298 | 0.70 | MAPK1 (0.43) | MEN1ALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL526369 | 0.70 | HRH4 (0.40) | MEN1ALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL401990 | 0.69 | PTGDR (0.36) | KDM1AMEN1KMT2A | |
| SCHEMBL404243 | 0.68 | TSHR (0.40) | WDR5MEN1ALDH1A1KMT2A | |
| SCHEMBL425877 | 0.68 | EPHX2 (0.50) | ALDH1A1MAOAMAOBALPLSLC6A4 | |
| SCHEMBL21381618 | 0.68 | KDM1A (0.43) | KDM1AALDH1A1MAOAMAOBALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8530388-B2 | Cyclopentadione derived herbicides | SYNGENTA LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-20120021912-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2389066-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | Syngenta Limited (GB) | 2011-11-30 | — | — | EP | disclosed |
| EP-2387310-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | Syngenta Limited (GB) | 2011-11-23 | — | — | EP | disclosed |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-D646956-S1 | TV mount | LEUNG ALEX | 2011-10-18 | — | — | US | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010081894-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021912-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | WDR5 1149/4885DDB1 1073/4885CRBN 3463/4885 |
| US-20110275515-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | DDT, CYP1B1, CYP1A1 | WDR5 2640/4885DDB1 1105/4885CRBN 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.