Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464075 | 0.89 | NPC1 (0.47) | CNR2SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4073305 | 0.87 | MAPT (0.35) | CNR2NPC1RAB9AMAPTHTT | |
| SCHEMBL1464745 | 0.86 | PKM (0.43) | CNR2PIK3C3RIOK2CNR1MAPK14 | |
| SCHEMBL4069812 | 0.78 | MEN1 (0.41) | CNR2SMN1; SMN2NPC1RAB9APIK3C3 | |
| SCHEMBL1465871 | 0.75 | CNR2 (0.53) | CNR2SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3960775 | 0.75 | CNR2 (0.42) | CNR2MAPTHSD17B10CNR1DUSP3 | |
| SCHEMBL1464740 | 0.73 | CNR2 (0.58) | CNR2PIK3C3RIOK2CNR1PKM | |
| SCHEMBL1464642 | 0.72 | CNR2 (0.54) | CNR2PIK3C3CNR1GRM4 | |
| SCHEMBL1463731 | 0.72 | AR (0.52) | CNR2PIK3C3CNR1DDR1ALDH1A1 | |
| SCHEMBL1465579 | 0.72 | ALDH1A1 (0.50) | CNR2MAPTHSD17B10DUSP3GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |