Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070531 | 0.87 | CNR2 (0.38) | MAPTALDH1A1KDM4EHPGDPIK3C3 | |
| SCHEMBL4069812 | 0.85 | MEN1 (0.41) | ALDH1A1PIK3C3MEN1KMT2ACNR2 | |
| SCHEMBL1464075 | 0.78 | NPC1 (0.47) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL1465943 | 0.75 | DHODH (0.55) | MAPTKDM4EMEN1KMT2ACNR2 | |
| SCHEMBL1464745 | 0.75 | PKM (0.43) | PIK3C3CNR2CNR1MAPK14 | |
| SCHEMBL1465181 | 0.74 | MEN1 (0.53) | MAPTALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL3960775 | 0.70 | CNR2 (0.42) | MAPTALDH1A1HPGDCNR2CNR1 | |
| SCHEMBL1465579 | 0.69 | ALDH1A1 (0.50) | MAPTALDH1A1HPGDCNR2GRM4 | |
| SCHEMBL1466234 | 0.66 | MEN1 (0.52) | MAPTALDH1A1KDM4ECYP2C9HPGD | |
| SCHEMBL1465871 | 0.66 | CNR2 (0.53) | MAPTALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |