SCHEMBL4070688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12032211	0.93	KIF11 (0.45)	KIF11ENPP1MAPTBACE1ALDH1A1
	SCHEMBL13085216	0.92	ENPP1 (0.49)	KIF11ENPP1MAPTTOP1
	SCHEMBL13016374	0.90	KIF11 (0.42)	KIF11ENPP1MAPTBACE1ALDH1A1
	SCHEMBL19003781	0.89	KIF11 (0.53)	KIF11ENPP1MAPTBACE1ALDH1A1
	SCHEMBL13085097	0.88	KIF11 (0.44)	KIF11ENPP1MAPTBACE1ALDH1A1
	SCHEMBL12032332	0.87	ENPP1 (0.43)	KIF11ENPP1ALDH1A1TDP1ESR1
	SCHEMBL4076119	0.86	ENPP1 (0.42)	ENPP1ALDH1A1TSHRESR1
	SCHEMBL13932229	0.85	KIF11 (0.52)	KIF11ENPP1MAPTBACE1ALDH1A1
	SCHEMBL13932230	0.85	KIF11 (0.52)	KIF11ENPP1MAPTBACE1ALDH1A1
	SCHEMBL13932278	0.85	KIF11 (0.45)	KIF11ENPP1MAPTBACE1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.