SCHEMBL4070866

SCHEMBL4070866

C=Cc1cccc(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 1/20 0.42
CA2 P00918 1/20 0.41
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28409231 0.87 ALDH1A1 (0.41) ALOX12CA2ALDH1A1TSHRTDP1
SCHEMBL10460047 0.84 ALOX12 (0.40) ALOX12CA2GABRA1GABRB2ALDH1A1
SCHEMBL4068356 0.81
SCHEMBL676429 0.81 ALOX12 (0.43) ALOX12CA2GABRA1GABRB2ALDH1A1
SCHEMBL29801228 0.80 ALDH1A1 (0.50) ALOX12CA2GABRA1GABRB2ALDH1A1
SCHEMBL27805 0.80 ALDH1A1 (0.50) ALOX12CA2GABRA1GABRB2ALDH1A1
SCHEMBL17261584 0.79 TDP1 (0.42) ALOX12CA2GABRA1GABRB2ALDH1A1
SCHEMBL9602139 0.79 ALOX12 (0.42) ALOX12CA2GABRA1GABRB2ALDH1A1
SCHEMBL10898322 0.79 GABRA1 (0.36) ALOX12CA2GABRA1GABRB2ALDH1A1
Benzene SCHEMBL11667348 0.78 ALDH1A1 (0.48) ALOX12CA2GABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100455615-C Arborescent thermoplastic elastomers and products therefrom UNIV WESTERN ONTARIO (CA) 2009-01-28 CN claimed
CN-1604923-A Arborescent thermoplastic elastomers and products thereof UNIV WESTERN ONTARIO (CA) 2005-04-06 CN claimed
US-6569953-B1 Oxyalkylation GEORGIA-PACIFIC RESINS, INC. 2003-05-27 US claimed
EP-0951496-B1 ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS GEORGIA PACIFIC RESINS (US) 2001-12-19 EP claimed
EP-0837892-B1 PHENOLIC POLYMERS MADE BY ARALKYLATION REACTIONS GEORGIA PACIFIC RESINS (US) 2001-11-14 EP claimed
US-6127491-A Phenolic resin polyols and polymers derived from the polyols GERORGIA-PACIFIC RESINS, INC. (US) 2000-10-03 US claimed
EP-0951496-A2 ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS GEORGIA-PACIFIC RESINS, INC. (US) 1999-10-27 EP claimed
CN-1196069-A Phenolic polymers made by aralkylation reactions GEORGIA PACIFIC RESINS (US) 1998-10-14 CN claimed
WO-1998030596-A2 ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS GEORGIA-PACIFIC RESINS, INC. (US) 1998-07-16 WO claimed
US-5770750-A Alkyd and aralkyd derivatives of phenolic polymers GEORGIA-PACIFIC RESINS, INC. (US) 1998-06-23 US claimed
EP-2019120-B1 BLOCK COPOLYMERS NIPPON SODA CO (JP) 2016-04-13 EP disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
CN-101443371-B Block copolymers NIPPON SODA CO 2011-09-07 CN disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
CN-101443371-A Block copolymers NIPPON SODA CO (JP) 2009-05-27 CN disclosed
WO-1998030596-A2 ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS GEORGIA-PACIFIC RESINS, INC. (US) 1998-07-16 WO disclosed
US-5770750-A Alkyd and aralkyd derivatives of phenolic polymers GEORGIA-PACIFIC RESINS, INC. (US) 1998-06-23 US disclosed
WO-1997019972-A1 PHENOLIC RESIN POLYOLS AND POLYMERS DERIVED FROM THE POLYOLS ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1997-06-05 WO disclosed
US-5119221-A Containing polymer adjustment layer MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-06-02 US disclosed
EP-0351718-A1 Liquid crystal display device comprising improved alignment layers for liquid crystal MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-01-24 EP disclosed