Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082522 | 0.96 | NLRP3 (0.32) | ALDH1A1TSHRNLRP3 | |
| SCHEMBL4070183 | 0.85 | CA2 (0.42) | NLRP3 | |
| SCHEMBL15529598 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL2487543 | 0.75 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL1161080 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL4006475 | 0.72 | — | — | |
| Acetonitrile SCHEMBL28114814 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TSHR | |
| SCHEMBL2489444 | 0.71 | NLRP3 (0.31) | NLRP3 | |
| Propane SCHEMBL8719519 | 0.70 | NLRP3 (0.37) | ALDH1A1TSHRNLRP3 | |
| SCHEMBL12410359 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625112-B1 | NOVEL COMPOUNDS FOR TREATMENT OF OBESITY | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1625112-A1 | NOVEL COMPOUNDS FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101505-A1 | NOVEL COMPOUNDS FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2004-11-25 | — | — | WO | disclosed |