Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073537 | 0.80 | ACHE (0.35) | CYP11B1CYP11B2IRAK4 | |
| SCHEMBL3858516 | 0.78 | CTSK (0.34) | IRAK4 | |
| SCHEMBL31380354 | 0.77 | CYP11B1 (0.38) | CYP11B1CYP11B2IRAK4 | |
| SCHEMBL4245388 | 0.75 | HRH4 (0.37) | IRAK4 | |
| SCHEMBL11855735 | 0.75 | KCNH2 (0.36) | IRAK4 | |
| SCHEMBL2363395 | 0.74 | KCNH2 (0.41) | IRAK4 | |
| SCHEMBL31380312 | 0.71 | MBOAT4 (0.33) | IRAK4 | |
| SCHEMBL3864358 | 0.71 | IRAK4 (0.44) | CYP11B1CYP11B2IRAK4 | |
| SCHEMBL2303573 | 0.71 | IRAK4 (0.37) | IRAK4 | |
| SCHEMBL5054743 | 0.71 | IRAK4 (0.44) | CYP11B1CYP11B2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784185-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1784185-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006028896-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |