Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080961 | 0.79 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL4075137 | 0.73 | MEN1 (0.43) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL4076976 | 0.72 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL18222999 | 0.59 | ALDH1A1 (0.67) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL1563556 | 0.56 | ALDH1A1 (0.59) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL1563011 | 0.56 | ALDH1A1 (0.59) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL4494644 | 0.56 | ALDH1A1 (0.71) | SMN1; SMN2MEN1KMT2ANPSR1MAPT | |
| SCHEMBL8324520 | 0.55 | MEN1 (0.57) | SMN1; SMN2MEN1KMT2AMAPTHPGD | |
| SCHEMBL135361 | 0.55 | KMT2A (0.50) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8583739 | 0.54 | MAPT (0.49) | LMNAMEN1KMT2ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |