Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076192 | 0.81 | KDM4E (0.45) | MEN1KMT2AATML3MBTL1MAPT | |
| SCHEMBL4071197 | 0.73 | LMNA (0.35) | MEN1KMT2AATML3MBTL1MAPT | |
| SCHEMBL27370614 | 0.73 | MAPT (0.51) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL27968518 | 0.69 | KDM4E (0.63) | MEN1KMT2AL3MBTL1MAPTKDM4E | |
| SCHEMBL4079956 | 0.69 | MTNR1A (0.42) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1061505 | 0.68 | KDM4E (0.67) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL4075252 | 0.64 | HDAC3 (0.44) | L3MBTL1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL13697479 | 0.64 | KDM4E (0.69) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL27825029 | 0.62 | ALDH1A1 (0.59) | MEN1KMT2AL3MBTL1MAPTKDM4E | |
| SCHEMBL8583739 | 0.62 | MAPT (0.49) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |