Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318727 | 0.88 | KDM4E (0.56) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL7350953 | 0.77 | HCRTR1 (0.50) | MEN1KMT2AATMRAB9ANPC1 | |
| SCHEMBL11406941 | 0.74 | KDM4E (0.57) | MEN1KMT2AATML3MBTL1ALDH1A1 | |
| SCHEMBL10980413 | 0.74 | KDM4E (0.57) | MEN1KMT2AATML3MBTL1ALDH1A1 | |
| SCHEMBL18941101 | 0.74 | HCRTR1 (0.73) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL2404460 | 0.74 | CYP4A11 (0.73) | RAB9ANPC1CYP4A11CYP4F2MAPT | |
| SCHEMBL7191192 | 0.74 | ALDH1A1 (0.60) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL7416657 | 0.73 | MEN1 (0.65) | MEN1KMT2AATML3MBTL1RAB9A | |
| SCHEMBL16010982 | 0.73 | CYP4A11 (0.53) | MEN1KMT2AALDH1A1HPGDCYP4A11 | |
| SCHEMBL28063129 | 0.72 | KIF11 (0.70) | MEN1KMT2AATML3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |