Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL29543519 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL109735 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL9770204 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL145053 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL4737418 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL4648043 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29683322 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29351424 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL4319 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL1532627 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3756642-B1 | METHOD TO INCREASE CELLULAR AVAILABILITY OF CALCIUM IN SKIN CELLS AND MIXTURES | MERCK PATENT GMBH (DE) | 2024-06-26 | — | — | EP | claimed |
| CN-112569162-B | Synergistic effect of radix Ophiopogonis extract, amino acid derivative and calcium lactate hydrate | 默克专利股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| US-11737997-B2 | Method to increase cellular availability of calcium in skin cells and mixtures | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | claimed |
| US-20220162113-A1 | BORATE-GLASS COMPOSITIONS, METHODS OF MANUFACTURE, AND USES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2022-05-26 | — | — | US | claimed |
| CN-111315241-B | Lactate powder and preparation method thereof | 普拉克生化公司 | 2022-04-26 | — | — | CN | claimed |
| EP-3947306-A1 | BORATE-GLASS COMPOSITIONS, METHODS OF MANUFACTURE, AND USES | The Royal Institution For The Advancement Of Learning/McGill University (CA) | 2022-02-09 | — | — | EP | claimed |
| CN-108157932-B | Double-screw extrusion mixing and drying-free preparation method of compound food additive lactic acid powder | 湖北壮美生物科技有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-112569162-A | Synergistic effect of ophiopogon root extract, amino acid derivative and calcium lactate hydrate | 默克专利股份有限公司 | 2021-03-30 | — | — | CN | claimed |
| US-20200405674-A1 | METHOD TO INCREASE CELLULAR AVAILABILITY OF CALCIUM IN SKIN CELLS AND MIXTURES | MERCK PATENT GMBH (DE) | 2020-12-31 | — | — | US | claimed |
| EP-3756642-A1 | METHOD TO INCREASE CELLULAR AVAILABILITY OF CALCIUM IN SKIN CELLS AND MIXTURES | Merck Patent GmbH (DE) | 2020-12-30 | — | — | EP | claimed |
| US-6080715-A | Granular compositions of .di-elect cons.-phthalimido peroxyhexanoic acid | AUSIMONT S.P.A. (IT) | 2000-06-27 | — | — | US | claimed |
| EP-0852259-A1 | Granular compositions of E-phthalimido peroxyhexanoic acid | Ausimont S.p.A. (IT) | 1998-07-08 | — | — | EP | claimed |
| EP-0563455-A1 | Particulate solid products containing a lump forming inhibitor | Purac Biochem B.V. (NL) | 1993-10-06 | — | — | EP | claimed |
| EP-0415567-A2 | Composition and method for stabilising organic compounds | QUADRANT BIORESOURCES LIMITED (GB) | 1991-03-06 | — | — | EP | claimed |
| EP-0396341-A2 | Agglomerated peroxyacid bleach granule and process for making same | THE PROCTER & GAMBLE COMPANY (US) | 1990-11-07 | — | — | EP | claimed |
| EP-0353281-A1 | METHOD OF DRYING MACROMOLECULES | QUADRANT BIORESOURCES LIMITED (GB) | 1990-02-07 | — | — | EP | claimed |
| CN-1037518-A | The drying means of macromolecular substance | QUADRANT BIORESOURCES LTD (GB) | 1989-11-29 | — | — | CN | claimed |
| WO-1989006976-A1 | METHOD OF DRYING MACROMOLECULES | QUADRANT BIORESOURCES LIMITED (GB) | 1989-08-10 | — | — | WO | claimed |
| US-4126573-A | DIPEROXYAZELAIC ACID OR DIPEROXYDODECANEDIOIC ACID PARTICLES COATED WITH A SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 1978-11-21 | — | — | US | claimed |
| US-4013773-A | VITAMIN E ACETATE OR CLOFIBRATE AND CALCIUM LACTATE HYDRATE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-03-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737997-B2 | Method to increase cellular availability of calcium in skin cells and mixtures | CA2, CHERP, SLC8B1 | TP53 211/4885CA1 26/4885CA4 173/4885 |
| US-20200405674-A1 | METHOD TO INCREASE CELLULAR AVAILABILITY OF CALCIUM IN SKIN CELLS AND MIXTURES | CA2, CHERP, ORAI1 | TP53 231/4885CA1 26/4885CA4 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.