Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIEZO1 | Q92508 | 5/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411641 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1411566 | 0.84 | PIEZO1 (0.49) | PIEZO1CHRNB4CHRNA3HPGDNPC1 | |
| SCHEMBL1411823 | 0.75 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL3899830 | 0.72 | CHRNB4 (0.44) | PIEZO1CHRNB4CHRNA3HPGDNPC1 | |
| SCHEMBL1411608 | 0.72 | PIEZO1 (0.36) | PIEZO1CHRNB4CHRNA3HPGDNPC1 | |
| SCHEMBL1410912 | 0.68 | P2RX7 (0.31) | — | |
| SCHEMBL1411043 | 0.68 | NPC1 (0.42) | PIEZO1HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL4078819 | 0.67 | PIEZO1 (0.33) | PIEZO1HPGDNPC1RAB9ANPSR1 | |
| SCHEMBL1411175 | 0.66 | CES1 (0.36) | — | |
| SCHEMBL1411527 | 0.65 | NPC1 (0.37) | PIEZO1HPGDNPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2112143-A1 | 2-(benzylsulfonyl)-oxazol-derivatives, chiral 2-(benzylsulfinyl]-oxazol derivatives, 2-(benzylsulfanyl-oxazol) derivatives, process for their preparation, as well as their use as herbicide and plant growth regulators | Bayer CropScience AG (DE) | 2009-10-28 | — | — | EP | disclosed |