Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072065 | 0.87 | PIEZO1 (0.39) | SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1411823 | 0.86 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL1410912 | 0.78 | P2RX7 (0.31) | — | |
| SCHEMBL1411175 | 0.76 | CES1 (0.36) | ADORA2A | |
| SCHEMBL11662024 | 0.71 | ALDH1A1 (0.39) | SMN1; SMN2TAAR1KMT2A | |
| SCHEMBL11530955 | 0.69 | — | — | |
| SCHEMBL1028747 | 0.68 | ALDH1A1 (0.36) | SMN1; SMN2ADORA2AADORA2BKMT2ALMNA | |
| SCHEMBL1411581 | 0.66 | TAAR1 (0.36) | TAAR1 | |
| SCHEMBL29163848 | 0.65 | — | — | |
| SCHEMBL1222337 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190125-A1 | 2-(BENZYLSULFONYL)OXAZOLE DERIVATIVES, CHIRAL 2-(BENZYLSULFINYL)OXAZOLE DERIVATIVES... | BAYER CROPSCIENCE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| EP-2294058-A1 | 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009129953-A1 | 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-10-29 | — | — | WO | disclosed |
| EP-2112143-A1 | 2-(benzylsulfonyl)-oxazol-derivatives, chiral 2-(benzylsulfinyl]-oxazol derivatives, 2-(benzylsulfanyl-oxazol) derivatives, process for their preparation, as well as their use as herbicide and plant growth regulators | Bayer CropScience AG (DE) | 2009-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190125-A1 | 2-(BENZYLSULFONYL)OXAZOLE DERIVATIVES, CHIRAL 2-(BENZYLSULFINYL)OXAZOLE DERIVATIVES... | BBOX1, STS, OXA1L | SMN1; SMN2 4022/4885TAAR1 2967/4885ADORA2A 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.