Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BCR | P11274 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079893 | 0.71 | G6PC1 (0.45) | G6PC1CYP1B1PTGS2ABL1BCR | |
| SCHEMBL10706017 | 0.65 | CHRM5 (0.63) | CYP1B1CYP1A1PTGS2NQO2ABL1 | |
| SCHEMBL13569071 | 0.64 | CYP1A2 (0.53) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL22925041 | 0.63 | CYP1B1 (0.52) | CYP1B1CYP1A1PTGS2NQO2ABL1 | |
| SCHEMBL13569101 | 0.63 | POLB (0.57) | BACE1KDM4EMEN1GAAMAPT | |
| SCHEMBL5383597 | 0.63 | CYP1B1 (0.47) | CYP1B1CYP1A1PTGS2NQO2ABL1 | |
| SCHEMBL5383595 | 0.63 | CYP1B1 (0.47) | CYP1B1CYP1A1PTGS2NQO2ABL1 | |
| SCHEMBL21386596 | 0.62 | CYP1B1 (0.56) | CYP1B1CYP1A1PTGS2NQO2ABCG2 | |
| SCHEMBL13128174 | 0.62 | CYP1B1 (0.56) | CYP1B1CYP1A1PTGS2NQO2ABL1 | |
| SCHEMBL6251820 | 0.62 | CYP1A1 (0.50) | CYP1B1CYP1A1PTGS2NQO2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |