Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073070 | 0.90 | G6PC1 (0.56) | G6PC1MEN1KMT2ACHRM5MAPT | |
| SCHEMBL4080914 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2ALMNAMAPTALOX12 | |
| SCHEMBL4074955 | 0.74 | MEN1 (0.41) | G6PC1MEN1KMT2ATSHRLMNA | |
| SCHEMBL1577336 | 0.74 | CRHBP (0.38) | MEN1KMT2ATSHRLMNAMAPT | |
| SCHEMBL4072093 | 0.71 | G6PC1 (0.41) | G6PC1ABL1BCRMEN1KMT2A | |
| SCHEMBL4789340 | 0.71 | MTNR1A (0.47) | LMNA | |
| SCHEMBL11838597 | 0.67 | TSHR (0.53) | G6PC1MEN1KMT2ATSHRMAPT | |
| SCHEMBL23346763 | 0.66 | CHRM5 (0.49) | G6PC1MEN1KMT2ACHRM5LMNA | |
| SCHEMBL6410526 | 0.66 | CA1 (0.44) | G6PC1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6410523 | 0.66 | CA1 (0.44) | G6PC1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |