Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 8/20 | 0.57 |
| ▸ | SRPK1 | Q96SB4 | 11/20 | 0.47 |
| ▸ | SRPK2 | P78362 | 10/20 | 0.45 |
| ▸ | SRPK3 | Q9UPE1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117639 | 0.84 | SRPK1 (0.43) | PTK2SRPK1SRPK2SRPK3 | |
| SCHEMBL407352 | 0.74 | AURKA (0.43) | — | |
| SCHEMBL14733008 | 0.73 | PTK2 (1.00) | PTK2SRPK1SRPK2SRPK3 | |
| SCHEMBL16967461 | 0.69 | PTK2 (1.00) | PTK2SRPK1SRPK2SRPK3 | |
| SCHEMBL12586298 | 0.68 | PTK2 (0.58) | PTK2SRPK1SRPK2SRPK3 | |
| SCHEMBL10171513 | 0.67 | AURKA (0.46) | — | |
| SCHEMBL407996 | 0.66 | AURKA (0.58) | — | |
| SCHEMBL30468452 | 0.66 | PTK2 (0.59) | PTK2SRPK1 | |
| Hydrochloric Acid SCHEMBL408995 | 0.66 | AURKA (0.45) | — | |
| Hydrochloric Acid SCHEMBL29051817 | 0.66 | PTK2 (0.58) | PTK2SRPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367822-B1 | TRICYCLIC AZAINDOLES | MERCK PATENT GMBH (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-8853391-B2 | Tricyclic azaindoles | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8853391-B2 | Tricyclic azaindoles | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-20120022060-A1 | Tricyclic Azaindoles | MERCK PATENT GMBH (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120022060-A1 | Tricyclic Azaindoles | MERCK PATENT GMBH (DE) | 2012-01-26 | — | — | US | disclosed |
| WO-2010080253-A1 | TRICYCLIC AZAINDOLES | MERCK PATENT GMBH (DE) | 2010-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022060-A1 | Tricyclic Azaindoles | AZI2, DCK, PPP2CA | PTK2 610/4885SRPK1 816/4885SRPK2 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.