Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 5/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063577 | 0.94 | LRRK2 (0.48) | LRRK2MAP2K1RAF1EGFRERBB2 | |
| SCHEMBL3151307 | 0.82 | LRRK2 (0.58) | LRRK2MAP2K1RAF1EGFRERBB2 | |
| SCHEMBL4246880 | 0.78 | LRRK2 (0.38) | LRRK2MAP2K1RAF1EGFRERBB2 | |
| SCHEMBL27668508 | 0.76 | TLR7 (0.47) | LRRK2MAP2K1RAF1TSHR | |
| SCHEMBL4572184 | 0.75 | LRRK2 (0.54) | LRRK2MAP2K1RAF1SRC | |
| SCHEMBL3156282 | 0.72 | LRRK2 (0.50) | LRRK2MAP2K1RAF1EGFRERBB2 | |
| SCHEMBL4231806 | 0.72 | LRRK2 (0.50) | LRRK2MAP2K1RAF1SRC | |
| SCHEMBL27668262 | 0.72 | LRRK2 (0.57) | LRRK2MAP2K1RAF1EGFRERBB2 | |
| SCHEMBL20178365 | 0.69 | LRRK2 (0.54) | LRRK2MAP2K1RAF1EGFRERBB2 | |
| SCHEMBL20494995 | 0.69 | ALDH1A1 (0.43) | LDHAMYCTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706412-A4 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK CHEMICALS CO LTD (KR) | 2009-03-18 | — | — | EP | disclosed |
| EP-1706412-A1 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK Chemicals, Co., Ltd. (KR) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005063768-A1 | NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SK CHEMICALS, CO., LTD. (KR) | 2005-07-14 | — | — | WO | disclosed |