Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | GMNN | O75496 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371269 | 0.92 | SLC6A5 (0.53) | LMNAMAPTSLC6A5ALDH1A1 | |
| SCHEMBL5153311 | 0.88 | LMNA (0.67) | LMNAMAPTSLC25A20TP53TSHR | |
| SCHEMBL7134196 | 0.88 | LMNA (0.67) | LMNAMAPTSLC25A20TP53TSHR | |
| SCHEMBL9105779 | 0.87 | LMNA (0.51) | LMNAMAPTSLC25A20TP53TSHR | |
| Hydrochloric Acid SCHEMBL243868 | 0.86 | LMNA (0.65) | LMNAMAPTSLC25A20TP53TSHR | |
| Hydrochloric Acid SCHEMBL5907094 | 0.86 | LMNA (0.65) | LMNAMAPTSLC25A20TP53TSHR | |
| SCHEMBL1800357 | 0.85 | MAPT (0.48) | LMNAMAPTSLC25A20TP53TSHR | |
| SCHEMBL18204276 | 0.85 | LMNA (0.47) | LMNAMAPTSLC25A20TP53TSHR | |
| SCHEMBL5824303 | 0.81 | SLC6A5 (0.50) | LMNAMAPTSLC6A5ALDH1A1 | |
| SCHEMBL6740155 | 0.80 | SLC6A5 (0.51) | MAPTSLC6A5MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021959-A1 | Muttiple Use Fabric Conditioning Composition With Blooming Perfume | MORGAN III GEORGE KAVIN (US) | 2012-01-26 | — | — | US | disclosed |
| US-20100331225-A1 | Multiple Use Fabric Conditioning Composition with Aminosilicone | THE PROCTER & GAMBLE COMPANY | 2010-12-30 | — | — | US | disclosed |
| US-7524809-B2 | Multiple use fabric conditioning composition with improved perfume | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-28 | — | — | US | disclosed |
| US-20050192204-A1 | Multiple use fabric conditioning composition with improved perfume | PROCTER & GAMBLE COMPANY, THE | 2005-09-01 | — | — | US | disclosed |