Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800357 | 0.93 | MAPT (0.48) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL16611500 | 0.91 | SLC6A5 (0.48) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL3371269 | 0.88 | SLC6A5 (0.53) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL5824303 | 0.84 | SLC6A5 (0.50) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL18204276 | 0.84 | LMNA (0.47) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL15956294 | 0.83 | MAPK1 (0.58) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL1027031 | 0.82 | LPAR3 (0.46) | CNR2FAAHALDH1A1CNR1 | |
| SCHEMBL29449493 | 0.81 | SLC6A5 (0.54) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL22319402 | 0.81 | SLC6A5 (0.54) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL14809228 | 0.81 | SLC6A5 (0.51) | SLC6A5PRKCAPRKCEPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680290-B1 | FABRIC SOFTENING FORMULATIONS, WHICH REMAIN CLEAR AT RELATIVELY LOW TEMPERATURES AND AT RELATIVELY LOW CONCENTRATIONS OF THE ACTIVE FABRIC SOFTENING INGREDIENT | DOW EUROPE S.A. (CH) | 2004-01-20 | — | — | US | disclosed |
| EP-1198548-A2 | CLEAR SOFTENING FORMULATIONS INCLUDING ALKOXYLATED ADDITIVES | THE DOW CHEMICAL COMPANY (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2002031094-A2 | CLEAR SOFTENING FORMULATIONS INCLUDING ALKOXYLATED ADDITIVES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| WO-2001002522-A2 | CLEAR SOFTENING FORMULATIONS INCLUDING ALKOXYLATED ADDITIVES | THE DOW CHEMICAL COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |