Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28202295 | 0.98 | TSHR (0.56) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28820918 | 0.88 | CA1 (0.44) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL9679649 | 0.81 | LMNA (0.61) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL5835571 | 0.81 | LMNA (0.61) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL15573246 | 0.81 | HSD17B10 (0.47) | LMNAALDH1A1TDP1HSD17B10KMT2A | |
| SCHEMBL15572350 | 0.81 | HSD17B10 (0.47) | LMNAALDH1A1TDP1HSD17B10KMT2A | |
| SCHEMBL15572208 | 0.81 | HSD17B10 (0.47) | LMNAALDH1A1TDP1HSD17B10KMT2A | |
| SCHEMBL15573214 | 0.81 | HSD17B10 (0.47) | LMNAALDH1A1TDP1HSD17B10KMT2A | |
| SCHEMBL23998048 | 0.78 | TPMT (0.46) | TDP1 | |
| SCHEMBL4737799 | 0.78 | CES2 (0.52) | TSHRLMNAF2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107686468-A | Contain the recovery method of the ketone of 1,2 benzisothiazole 3 in a kind of solvent | 连云港市三联化工有限公司 | 2018-02-13 | — | — | CN | claimed |
| CN-107602501-A | The synthetic method of the ketone of 1,2 benzisothiazole of N normal-butyls 3 | 连云港市三联化工有限公司 | 2018-01-19 | — | — | CN | claimed |
| CN-103694194-A | Synthesis method of 2-methyl-1, 2-benzisothiazolin-3-ketone | SHOUGUANG SYNTECH FINE CHEMICAL CO LTD | 2014-04-02 | — | — | CN | claimed |
| CN-103664817-A | Synthesis method for 2-butyl-1, 2-benzisothiazolin-3-ketone | SHOUGUANG XINTAI FINE CHEMICAL CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-101817770-B | Method for preparing methylthio-benzoic acid | UNIV JIANGSU POLYTECHNIC | 2013-06-19 | — | — | CN | claimed |
| CN-101712641-B | Method for preparing methylthio benzoic acid | UNIV JIANGSU POLYTECHNIC | 2013-05-08 | — | — | CN | claimed |
| CN-101817770-A | Method for preparing methylthio-benzoic acid | UNIV JIANGSU POLYTECHNIC | 2010-09-01 | — | — | CN | claimed |
| CN-101712641-A | Method for preparing methylthio benzoic acid | UNIV JIANGSU POLYTECHNIC | 2010-05-26 | — | — | CN | claimed |
| CN-116634871-A | Pesticidal compounds and compositions, methods of use and methods of preparation thereof | 阿达玛马克西姆有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116283785-A | Sulfhydryl compound and preparation method thereof | 华能武汉发电有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-11382924-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2022-07-12 | — | — | US | disclosed |
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |
| EP-3849972-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THERE OF | Betta Pharmaceuticals Co., Ltd (CN) | 2021-07-21 | — | — | EP | disclosed |
| CN-101817770-A | Method for preparing methylthio-benzoic acid | UNIV JIANGSU POLYTECHNIC | 2010-09-01 | — | — | CN | disclosed |
| CN-101712641-A | Method for preparing methylthio benzoic acid | UNIV JIANGSU POLYTECHNIC | 2010-05-26 | — | — | CN | disclosed |
| EP-2084136-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008065907-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-06-05 | — | — | WO | disclosed |
| EP-1644334-A1 | ANTITHROMBOTIC ETHERS | Eli Lilly and Company (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004108677-A1 | ANTITHROMBOTIC ETHERS | ELI LILLY AND COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | FUT6, DDOST, MGAM | TSHR 2609/4885LMNA 1332/4885F2 4876/4885 |
| US-11382924-B2 | Compounds and pharmaceutical uses thereof | ACE, ACE2, FURIN | TSHR 4243/4885LMNA 2707/4885F2 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.