Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichlorobenzene SCHEMBL23407542 | 0.84 | TSHR (0.67) | LMNATSHRALDH1A1ADRB2ADRB1 | |
| 1,2-Dichlorobenzene SCHEMBL28433310 | 0.79 | TSHR (0.83) | LMNATSHRALDH1A1CES2CES1 | |
| 1,2-Dichlorobenzene SCHEMBL10593125 | 0.79 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL5190 | 0.79 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL1155123 | 0.79 | TSHR (1.00) | LMNATSHRALDH1A1CES2CES1 | |
| 1,2-Dichlorobenzene SCHEMBL29350623 | 0.79 | — | — | |
| Chlorobenzene SCHEMBL10495324 | 0.79 | TSHR (0.65) | LMNATSHRALDH1A1ADRB2CES2 | |
| SCHEMBL342944 | 0.78 | ADRB2 (0.55) | LMNATSHRALDH1A1ADRB2ADRB1 | |
| SCHEMBL504837 | 0.78 | ADRB2 (0.55) | LMNATSHRALDH1A1ADRB2ADRB1 | |
| SCHEMBL316799 | 0.78 | ADRB2 (0.55) | LMNATSHRALDH1A1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081921-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008007071-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | CENES LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |