SCHEMBL407278

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL410962	0.91	ALDH1A1 (0.42)	LMNAPOLBALDH1A1SMN1; SMN2TUBB4A
	SCHEMBL411754	0.91	TUBB4A (0.44)	LMNAPOLBALDH1A1SMN1; SMN2TUBB4A
	SCHEMBL411779	0.89	PTGS1 (0.49)	LMNAPOLBALDH1A1SMN1; SMN2TUBB4A
	SCHEMBL413876	0.86	SMN1; SMN2 (0.45)	LMNAPOLBALDH1A1SMN1; SMN2TUBB1
	SCHEMBL412205	0.84	ALDH1A1 (0.48)	LMNAPOLBALDH1A1SMN1; SMN2PTGS1
	SCHEMBL410992	0.84	ALDH1A1 (0.44)	LMNAPOLBALDH1A1SMN1; SMN2TUBB4A
	SCHEMBL410897	0.83	ALDH1A1 (0.47)	LMNAPOLBALDH1A1SMN1; SMN2TUBB4A
	SCHEMBL408302	0.83	ALDH1A1 (0.47)	LMNAPOLBALDH1A1SMN1; SMN2TUBB4A
	SCHEMBL411397	0.83	ALDH1A1 (0.47)	POLBALDH1A1SMN1; SMN2PTGS1PTGS2
	SCHEMBL411261	0.82	PTK2 (0.43)	POLBALDH1A1SMN1; SMN2TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.