Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | UQCRB | P14927 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067709 | 0.89 | SERPINE1 (0.49) | PTPN5ALDH1A1KDM4ELMNABRD4 | |
| SCHEMBL4072961 | 0.88 | PTPN5 (0.45) | PTPN5ALDH1A1KDM4ELMNABRD4 | |
| SCHEMBL4077705 | 0.86 | PTPN5 (0.41) | PTPN5ALDH1A1KDM4ELMNABRD4 | |
| SCHEMBL4073082 | 0.82 | SERPINE1 (0.48) | PTPN5ALDH1A1KDM4ELMNABRD4 | |
| SCHEMBL4069882 | 0.82 | BRD4 (0.42) | PTPN5ALDH1A1KDM4ELMNABRD4 | |
| SCHEMBL4072264 | 0.80 | EDNRB (0.46) | PTPN5LMNAHIF1AMEN1KMT2A | |
| SCHEMBL4392130 | 0.80 | SERPINE1 (0.47) | PTPN5ALDH1A1KDM4ELMNABRD4 | |
| SCHEMBL4070333 | 0.80 | FABP1 (0.45) | ALDH1A1KDM4EPOLBHTR1AHTR1D | |
| SCHEMBL4067259 | 0.78 | SERPINE1 (0.46) | PTPN5ALDH1A1KDM4ELMNABRD4 | |
| SCHEMBL4137983 | 0.78 | HTR1A (0.37) | PTPN5ALDH1A1KDM4ELMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |