Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TNKS | O95271 | 3/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441020 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TNKSPARP2PARP1VCP | |
| SCHEMBL406906 | 0.87 | NPC1 (0.53) | ALDH1A1TNKSPARP2PARP1CYP2C19 | |
| SCHEMBL440037 | 0.87 | NPC1 (0.53) | ALDH1A1TNKSPARP2PARP1CYP2C19 | |
| SCHEMBL439177 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TNKSPARP2PARP1PTGS2 | |
| SCHEMBL408370 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TNKSPARP2PARP1PTGS2 | |
| Trifluoroacetic Acid SCHEMBL16989785 | 0.79 | ALDH1A1 (0.60) | ALDH1A1TNKSPARP2PARP1PTGS2 | |
| SCHEMBL408850 | 0.79 | AKR1C3 (0.53) | ALDH1A1TNKSPARP2CYP2C19KDM4E | |
| SCHEMBL29988207 | 0.78 | ALDH1A1 (0.66) | ALDH1A1TNKSPARP2PARP1CYP2C19 | |
| Bromide SCHEMBL2710523 | 0.78 | ALDH1A1 (0.73) | ALDH1A1TNKSPARP2PARP1CYP2C19 | |
| SCHEMBL6125254 | 0.78 | ALDH1A1 (0.73) | ALDH1A1TNKSPARP2PARP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | ALDH1A1 272/4885TNKS 4718/4885PARP2 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.