Phenanthroline

Phenanthroline

SCHEMBL407390

c1ccncc1.c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.76
CCR8 P51685 5/20 0.76
LMNA P02545 4/20 0.76
KDM4E B2RXH2 4/20 0.76
CCR5 P51681 3/20 0.76
TSHR P16473 3/20 0.76
TDP1 Q9NUW8 3/20 0.76
MMP2 P08253 2/20 0.76
MAPT P10636 2/20 0.76
HTT P42858 2/20 0.76
SMN1; SMN2 Q16637 2/20 0.76
HSP90AA1 P07900 2/20 0.76
GMNN O75496 1/20 0.76
TP53 P04637 1/20 0.76
CYP3A4 P08684 1/20 0.76
CYP2D6 P10635 1/20 0.76
MMP9 P14780 1/20 0.76
ALOX15 P16050 1/20 0.76
NFKB1 P19838 1/20 0.76
MMP8 P22894 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthroline SCHEMBL28719970 0.90 CCR1 (0.84) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL28130373 0.90 CCR1 (0.94) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL28634595 0.90 KDM4E (0.61) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL29354015 0.87 CCR1 (1.00) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL29367277 0.87 CCR1 (1.00) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL8312 0.87 CCR1 (1.00) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL8845760 0.87 CCR1 (1.00) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL9343811 0.85 KDM4E (0.84) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL22982126 0.85 CCR1 (0.94) CCR1CCR8LMNAKDM4ECCR5
Phenanthroline SCHEMBL21044608 0.85 CCR1 (0.94) CCR1CCR8LMNAKDM4ECCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5902901-A Arylamine processes XEROX CORPORATION (US) 1999-05-11 US claimed
EP-0856508-A1 Processes for the preparation of arylamines XEROX CORPORATION (US) 1998-08-05 EP claimed
US-5723671-A Arylamine processes XEROX CORPORATION (US) 1998-03-03 US claimed
US-5723669-A Arylamine processes XEROX CORPORATION (US) 1998-03-03 US claimed
US-5705697-A ULLMAN CONDENSATION OF IODOXYLENE WITH N-(3,4-DIMETHYLPHENYL)-4-BIPHENYLAMINE CATALYZED BY COPPER/I/ COMPLEXED TO NITROGEN-CONTAINING HETEROARYL LIGAND XEROX CORPORATION (US) 1998-01-06 US claimed
US-5648539-A REACTION OF METHYLDIPHENYLAMINE OR METHOXYDIPHENYLAMINE AND DIIODOBIPHENYL, LIGATED COPPER CATALYST XEROX CORPORATION (US) 1997-07-15 US claimed
US-5648542-A COPPER CATALYST XEROX CORPORATION (US) 1997-07-15 US claimed
CN-116713021-A Method for preparing sub-nano-scale copper catalyst by combining coordination complexing and space limitation 云南师范大学 2023-09-08 CN disclosed
CN-106458958-B Herbicidal propynyl-phenyl compounds 先正达参股股份有限公司 2020-07-10 CN disclosed
US-10696686-B2 Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof SYNGENTA LIMITED (GB) 2020-06-30 US disclosed
US-10662138-B2 Herbicidal propynyl-phenyl compounds SYNGENTA PARTICIPATIONS AG (CH) 2020-05-26 US disclosed
EP-3160950-B1 HERBICIDAL PROPYNYL-PHENYL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2020-05-13 EP disclosed
US-10590143-B2 Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof SYNGENTA LIMITED (GB) 2020-03-17 US disclosed
US-20100279872-A1 4-PHENYLPYRANE-3,5-DIONES, 4-PHENYLTHIOPYRANE-3,5-DIONES AND 2-PHENYLCYCLOHEXANE-1,3,5-TRIONES AS HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-11-04 US disclosed
US-20100210466-A1 4-PHENYL-PYRANE-3,5-DIONES,4-PHENYL-THIOPYRANE-3,6-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-08-19 US disclosed
CN-101605771-A 4-phenyl-pyran-3, 5-diones, 4-phenyl-thiopyran-3, 5-diones and cyclohexanetriones as novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2009-12-16 CN disclosed
US-5902901-A Arylamine processes XEROX CORPORATION (US) 1999-05-11 US disclosed
EP-0856508-A1 Processes for the preparation of arylamines XEROX CORPORATION (US) 1998-08-05 EP disclosed
US-5723671-A Arylamine processes XEROX CORPORATION (US) 1998-03-03 US disclosed
US-5723669-A Arylamine processes XEROX CORPORATION (US) 1998-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210466-A1 4-PHENYL-PYRANE-3,5-DIONES,4-PHENYL-THIOPYRANE-3,6-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES DDT, HPD, CYP4B1 CCR1 3300/4885CCR8 2625/4885LMNA 4842/4885
US-10696686-B2 Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof DDT, CNPY2, CNPY3 CCR1 559/4885CCR8 1084/4885LMNA 2448/4885
US-10662138-B2 Herbicidal propynyl-phenyl compounds CBR3, CBR1, CNPY3 CCR1 267/4885CCR8 143/4885LMNA 4526/4885
US-20100279872-A1 4-PHENYLPYRANE-3,5-DIONES, 4-PHENYLTHIOPYRANE-3,5-DIONES AND 2-PHENYLCYCLOHEXANE-1,3,5-TRIONES AS HERBICIDES DDT, HPD, THOP1 CCR1 2216/4885CCR8 2353/4885LMNA 4797/4885
US-10590143-B2 Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof DDT, CNPY2, TET1 CCR1 593/4885CCR8 1105/4885LMNA 2568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.