Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.46 |
| ▸ | SRC | P12931 | 4/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085096 | 1.00 | HTT (0.48) | HTTALDH1A1TPSAB1TPSD1TPSG1 | |
| SCHEMBL4073907 | 1.00 | HTT (0.48) | HTTALDH1A1TPSAB1TPSD1TPSG1 | |
| SCHEMBL4077352 | 0.80 | CASP3 (0.52) | ALDH1A1 | |
| SCHEMBL4077350 | 0.80 | CASP3 (0.52) | ALDH1A1 | |
| SCHEMBL4078596 | 0.80 | CASP3 (0.52) | ALDH1A1 | |
| SCHEMBL4963843 | 0.80 | CA1 (0.42) | HTTALDH1A1DDB1CRBN | |
| SCHEMBL4074445 | 0.79 | DPP4 (0.44) | — | |
| SCHEMBL4078074 | 0.79 | DPP4 (0.44) | — | |
| SCHEMBL4074441 | 0.79 | DPP4 (0.44) | — | |
| SCHEMBL4082421 | 0.77 | CASP3 (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531657-B2 | Method for preparing sulphostin and analogue thereof or preparation intermediate thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20050020834-A1 | Method for preparation of sulphostin and its analogue or intermediates thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1457494-A1 | PROCESSES FOR PREPARATION OF SULPHOSTIN AND ITS ANALOGUES OR INTERMEDIATES THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2004-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020834-A1 | Method for preparation of sulphostin and its analogue or intermediates thereof | SOST, PTMS, FGF23 | HTT 3685/4885ALDH1A1 3724/4885TPSAB1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.