Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | OGG1 | O15527 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836138 | 0.79 | CYP3A4 (0.53) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL4079410 | 0.79 | HDAC1 (0.49) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL4411483 | 0.78 | HDAC3 (0.44) | CYP3A4BLMPMP22HIF1AHDAC8 | |
| SCHEMBL31454334 | 0.77 | HDAC6 (0.74) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL10561443 | 0.76 | MPO (0.59) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL4071505 | 0.76 | MPO (0.50) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL4079534 | 0.76 | TPSAB1 (0.59) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL4071375 | 0.73 | ATM (0.53) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL343630 | 0.73 | MPO (0.80) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL2678949 | 0.73 | MPO (0.80) | MPOCYP3A4KDM5ABLMGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |