Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18422592 | 0.81 | CYP1A2 (0.55) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL10561443 | 0.79 | MPO (0.59) | HDAC1HDAC6HDAC3HDAC8CA1 | |
| SCHEMBL21454774 | 0.79 | HDAC6 (0.75) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL2832296 | 0.77 | MAPT (0.72) | CA1CA2CYP3A4MAPTKDM4E | |
| SCHEMBL4074049 | 0.76 | MPO (0.47) | HDAC1HDAC6HDAC8CA1CA2 | |
| SCHEMBL343630 | 0.76 | MPO (0.80) | HDAC6HDAC3CA1CA2MPO | |
| SCHEMBL2678949 | 0.76 | MPO (0.80) | HDAC6HDAC3CA1CA2MPO | |
| SCHEMBL11139882 | 0.74 | MPO (0.64) | HDAC1HDAC6HDAC3CA1CA2 | |
| SCHEMBL2836138 | 0.74 | CYP3A4 (0.53) | HDAC1CA1CA2MPOCYP3A4 | |
| SCHEMBL28188923 | 0.73 | MPO (0.76) | HDAC6HDAC3CA1CA2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |