Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074180 | 1.00 | F10 (0.43) | F10GPR119F2CHEK2PDE4A | |
| SCHEMBL3899270 | 0.87 | GPR119 (0.48) | F10GPR119F2CHEK2PDE4A | |
| SCHEMBL3899273 | 0.87 | GPR119 (0.48) | F10GPR119F2CHEK2PDE4A | |
| SCHEMBL3894603 | 0.76 | RORC (0.40) | GPR119CHEK2MAPT | |
| SCHEMBL3897950 | 0.76 | GPR119 (0.56) | F10GPR119F2PDE4APDE4B | |
| SCHEMBL3912286 | 0.75 | F10 (0.60) | F10GPR119F2L3MBTL1 | |
| SCHEMBL6873900 | 0.75 | GPR119 (0.51) | F10GPR119F2CHEK2L3MBTL1 | |
| SCHEMBL6873899 | 0.75 | GPR119 (0.51) | F10GPR119F2CHEK2L3MBTL1 | |
| SCHEMBL6864795 | 0.73 | GPR119 (0.51) | F10GPR119F2CHEK2PDE4A | |
| SCHEMBL6864800 | 0.73 | GPR119 (0.51) | F10GPR119F2CHEK2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |