Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899270 | 1.00 | GPR119 (0.48) | GPR119F10F2CHEK2ALK | |
| SCHEMBL3894603 | 0.90 | RORC (0.40) | GPR119CHEK2CCNCCDK8HDAC1 | |
| SCHEMBL3894607 | 0.90 | RORC (0.40) | GPR119CHEK2CCNCCDK8HDAC1 | |
| SCHEMBL4074180 | 0.87 | F10 (0.43) | GPR119F10F2CHEK2PDE4A | |
| SCHEMBL4074181 | 0.87 | F10 (0.43) | GPR119F10F2CHEK2PDE4A | |
| SCHEMBL6873899 | 0.86 | GPR119 (0.51) | GPR119F10F2CHEK2ALK | |
| SCHEMBL6873900 | 0.86 | GPR119 (0.51) | GPR119F10F2CHEK2ALK | |
| SCHEMBL6864795 | 0.84 | GPR119 (0.51) | GPR119F10F2CHEK2ALK | |
| SCHEMBL6864800 | 0.84 | GPR119 (0.51) | GPR119F10F2CHEK2ALK | |
| SCHEMBL6555091 | 0.83 | GPR119 (0.50) | GPR119F10F2CHEK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |