Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of 3-Methylpyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylpyridine SCHEMBL7852996 | 0.92 | NAPRT (0.52) | NAPRTCYP2A6CYP3A4PTGS2EGFR | |
| 3-Methylpyridine SCHEMBL9336426 | 0.90 | NAPRT (0.50) | NAPRTCYP2A6CYP3A4PTGS2EGFR | |
| 3-Methylpyridine SCHEMBL28292293 | 0.89 | NAPRT (0.46) | NAPRTCYP2A6CYP3A4PTGS2EGFR | |
| 3-Methylpyridine SCHEMBL27365504 | 0.87 | CYP2A6 (0.48) | NAPRTCYP2A6CYP3A4PTGS2EGFR | |
| Trifluoromethanesulfonic Acid SCHEMBL30580567 | 0.87 | NAPRT (0.47) | NAPRTCYP2A6CYP3A4PTGS2EGFR | |
| Trifluoromethanesulfonic Acid SCHEMBL27649544 | 0.87 | NAPRT (0.47) | NAPRTCYP2A6CYP3A4PTGS2EGFR | |
| 3-Methylpyridine SCHEMBL29046452 | 0.86 | — | — | |
| 3-Methylpyridine SCHEMBL29361018 | 0.86 | — | — | |
| 3-Methylpyridine SCHEMBL820155 | 0.86 | CYP2A6 (0.54) | CYP2A6CYP3A4ALDH1A1NPC1RAB9A | |
| 3-Methylpyridine SCHEMBL10530 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423595-B1 | Process for the preparation of 3-trichloromethyl pyridine | BAYER AG (DE) | 1994-05-18 | — | — | EP | claimed |
| US-5091068-A | PREPARATION OF 3-TRICHLOROMETHYL-PYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | claimed |
| EP-0423595-A2 | Process for the preparation of 3-trichloromethyl pyridine | BAYER AG (DE) | 1991-04-24 | — | — | EP | claimed |
| JP-3135956-A | — | — | None | — | — | JP | disclosed |
| US-12279617-B2 | Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient | AGRO-KANESHO CO., LTD. (JP) | 2025-04-22 | — | — | US | disclosed |
| WO-2025018390-A1 | NOVEL HYDRAZONE DERIVATIVE AND AGENT FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING SAME AS ACTIVE INGREDIENT | アグロカネショウ株式会社 | 2025-01-23 | — | — | WO | disclosed |
| EP-3985004-B1 | AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT | AGRO KANESHO CO LTD (JP) | 2024-09-04 | — | — | EP | disclosed |
| WO-2024117205-A1 | BICYCLIC PYRIDINE DERIVATIVE AND SALT THEREOF, AND HARMFUL ORGANISM CONTROL AGENT CHARACTERIZED BY CONTAINING SAID DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 北興化学工業株式会社 | 2024-06-06 | — | — | WO | disclosed |
| US-11903388-B2 | Lichen compounds that inhibit mycotoxin production | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2024-02-20 | — | — | US | disclosed |
| US-20230292766-A1 | Biocontrol of Fusarium by Endophytic Fungi | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2023-09-21 | — | — | US | disclosed |
| US-20220330550-A1 | AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAINING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT | AGRO-KANESHO CO., LTD. (JP) | 2022-10-20 | — | — | US | disclosed |
| US-5760033-A | INSECTICDES; MITICIDES | NIPPON SODA CO., LTD (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0717039-A1 | NOVEL TRIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0675115-A1 | HETEROCYCLIC DERIVATIVE AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |
| EP-0423595-B1 | Process for the preparation of 3-trichloromethyl pyridine | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| US-5091068-A | PREPARATION OF 3-TRICHLOROMETHYL-PYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5091068-A | PREPARATION OF 3-TRICHLOROMETHYL-PYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| JP-H03135956-A | PRODUCTION OF 3-TRICHLOROMETHYL-PYRIDINE | BAYER AG | 1991-06-10 | — | — | JP | disclosed |
| EP-0423595-A2 | Process for the preparation of 3-trichloromethyl pyridine | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |
| EP-0423595-A2 | Process for the preparation of 3-trichloromethyl pyridine | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12279617-B2 | Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient | CBR3, HRH4, H1-0 | NAPRT 2321/4885CYP2A6 1315/4885CYP3A4 1277/4885 |
| US-11903388-B2 | Lichen compounds that inhibit mycotoxin production | LSS, ERG28, LTA | NAPRT 199/4885CYP2A6 3255/4885CYP3A4 3038/4885 |
| US-20220330550-A1 | AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAINING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT | CBR3, HRH4, H1-0 | NAPRT 2590/4885CYP2A6 1631/4885CYP3A4 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.