Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26705603 | 0.84 | RAB9A (0.40) | RAB9AMEN1HPGDKMT2ACYP2D6 | |
| SCHEMBL5407237 | 0.82 | MEN1 (0.52) | RAB9AMEN1HPGDKMT2AKIT | |
| SCHEMBL12233216 | 0.82 | RAB9A (0.51) | RAB9AMEN1HPGDKMT2AKIT | |
| SCHEMBL3768429 | 0.80 | KMT2A (0.55) | RAB9AMEN1HPGDKMT2AKIT | |
| SCHEMBL3663186 | 0.80 | CYP2D6 (0.42) | RAB9AMEN1HPGDKMT2ACYP2D6 | |
| SCHEMBL18932497 | 0.78 | RAB9A (0.40) | RAB9AMEN1HPGDKMT2ACYP2D6 | |
| SCHEMBL4008393 | 0.77 | RAB9A (0.41) | RAB9AMEN1HPGDKMT2ACYP2C9 | |
| SCHEMBL895343 | 0.77 | L3MBTL1 (0.55) | MEN1KMT2AL3MBTL1ALDH1A1CHRM1 | |
| SCHEMBL3955003 | 0.76 | CYP2D6 (0.39) | RAB9AMEN1HPGDKMT2ACYP2D6 | |
| SCHEMBL1127578 | 0.75 | GAA (0.39) | RAB9AMEN1HPGDKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796793-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1796793-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006029154-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |