Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956031 | 0.80 | JAK2 (0.37) | CYP2D6RAB9AKITJAK2JAK1 | |
| SCHEMBL6208321 | 0.78 | L3MBTL1 (0.40) | CYP2D6RAB9AKITJAK2JAK1 | |
| SCHEMBL3663186 | 0.76 | CYP2D6 (0.42) | CYP2D6RAB9AKITJAK2JAK1 | |
| SCHEMBL4074787 | 0.76 | RAB9A (0.41) | CYP2D6RAB9AKITJAK2JAK1 | |
| SCHEMBL926934 | 0.75 | HRH2 (0.42) | RAB9AKITHRH2HRH1MEN1 | |
| SCHEMBL26705603 | 0.75 | RAB9A (0.40) | CYP2D6RAB9AKITJAK2JAK1 | |
| SCHEMBL5407237 | 0.75 | MEN1 (0.52) | RAB9AKITL3MBTL1HRH2HRH1 | |
| SCHEMBL12233216 | 0.75 | RAB9A (0.51) | RAB9AKITL3MBTL1HRH2HRH1 | |
| SCHEMBL29269482 | 0.74 | RAB9A (0.46) | RAB9AKITJAK2JAK1L3MBTL1 | |
| SCHEMBL23551896 | 0.74 | CYP2D6 (0.47) | CYP2D6RAB9AKITJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784410-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-07-15 | — | — | EP | disclosed |
| EP-1784410-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006020561-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-02-23 | — | — | WO | disclosed |