Pyridine

Pyridine

SCHEMBL4074944

F.F.F.F.F.F.[SbH3].c1ccncc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.82
NAPRT Q6XQN6 1/20 0.82
TDP1 Q9NUW8 1/20 0.82
NOTUM Q6P988 1/20 0.37
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL27901621 0.95
Pyridine SCHEMBL9514761 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL28721156 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL9514765 0.95
Pyridine SCHEMBL97170 0.95
Pyridine SCHEMBL29109706 0.95
Pyridine SCHEMBL28181242 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL23141434 0.91
Pyridine SCHEMBL17966108 0.91 TSHR (0.82) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL23093671 0.91 TSHR (0.82) TSHRNAPRTTDP1NOTUMSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791824-B1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO KK (JP) 2009-08-05 EP disclosed
US-20090192279-A1 Radically Polymerizable Sulfur-Containing Compound and Radically Polymerizable Sulfur-Containing Polymer SHOWA DENKO K.K. (JP) 2009-07-30 US disclosed
US-7518001-B2 Radically polymerizable sulfur-containing compound and radically polymerizable sulfur-containing polymer SHOWA DENKO K.K. (JP) 2009-04-14 US disclosed
US-20070208149-A1 Radically Polymerizable Sulfur-Containing Compound And Radically Polymerizable Sulfur-Containing Polymer SHOWA DENKO K.K. (JP) 2007-09-06 US disclosed
EP-1791824-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER Showa Denko K.K. (JP) 2007-06-06 EP disclosed
WO-2006033438-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO K.K. (JP) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208149-A1 Radically Polymerizable Sulfur-Containing Compound And Radically Polymerizable Sulfur-Containing Polymer CBS, TST, MSRB3 TSHR 4037/4885NAPRT 4110/4885TDP1 4410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.