Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655578 | 0.84 | SLC2A1 (0.49) | ABCG2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3217690 | 0.79 | PRMT1 (0.50) | ABCG2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2558030 | 0.78 | ALDH1A1 (0.57) | ABCG2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5733923 | 0.76 | ABCG2 (0.50) | ABCG2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1557504 | 0.75 | KDM4E (0.55) | ABCG2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6008353 | 0.74 | ABCG2 (0.65) | ABCG2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL170690 | 0.72 | ERN1 (0.55) | ABCG2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL12668729 | 0.69 | SLC2A1 (0.62) | ABCG2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL11766181 | 0.69 | KDM4E (0.46) | ABCG2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27685686 | 0.69 | ERN1 (0.52) | ABCG2ALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2083818-A2 | MELATONIN DERIVATIVES AND THEIR USE AS ANTIOXIDANTS | University of Sunderland (GB) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008062167-A2 | MELATONIN DERIVATIVES AND THEIR USE AS ANTIOXIDANTS | UNIVERSITY OF SUNDERLAND (GB) | 2008-05-29 | — | — | WO | disclosed |