SCHEMBL4075002

SCHEMBL4075002

CC(=O)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
KMT2A Q03164 4/20 0.90
MEN1 O00255 3/20 0.72
POLB P06746 1/20 0.72
ALDH1A1 P00352 6/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
GAA P10253 3/20 0.68
MAPK1 P28482 1/20 0.68
MAPT P10636 2/20 0.67
PKM P14618 1/20 0.67
USP2 O75604 1/20 0.67
LMNA P02545 1/20 0.67
ABCC9 O60706 1/20 0.65
ABCC8 Q09428 1/20 0.65
KCNJ11 Q14654 1/20 0.65
KCNJ8 Q15842 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3300404 0.86 ALDH1A1 (0.84) L3MBTL1KMT2AMEN1ALDH1A1GAA
SCHEMBL19277768 0.86 L3MBTL1 (0.74) L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL12490995 0.85 L3MBTL1 (0.74) L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL4070839 0.85 ALDH1A1 (0.84) L3MBTL1KMT2AMEN1ALDH1A1GAA
SCHEMBL12793391 0.85 GAA (0.79) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL8644045 0.85 ALDH1A1 (0.81) L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL4759272 0.84 KMT2A (0.78) L3MBTL1KMT2AMEN1ALDH1A1GAA
SCHEMBL12386394 0.83 L3MBTL1 (0.71) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL12010889 0.83 ALDH1A1 (0.78) L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL12386393 0.82 KMT2A (0.72) L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 EP claimed
US-20090233878-A1 NOVEL ADENOSINE A3 RECEPTOR AGONISTS CREDIT SUISSE AG 2009-09-17 US disclosed
US-20090233878-A1 NOVEL ADENOSINE A3 RECEPTOR AGONISTS CREDIT SUISSE AG 2009-09-17 US disclosed
US-20090233878-A1 NOVEL ADENOSINE A3 RECEPTOR AGONISTS CREDIT SUISSE AG 2009-09-17 US disclosed
US-7511133-B2 Adenosine A3 receptor agonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2009-03-31 US disclosed
US-7511133-B2 Adenosine A3 receptor agonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2009-03-31 US disclosed
US-7511133-B2 Adenosine A3 receptor agonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2009-03-31 US disclosed
US-20050250729-A1 Novel adenosine A3 receptor agonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. 2005-11-10 US disclosed
WO-2002078970-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233878-A1 NOVEL ADENOSINE A3 RECEPTOR AGONISTS ADORA3, ADORA1, ADORA2A L3MBTL1 2235/4885KMT2A 1872/4885MEN1 3593/4885
US-20050250729-A1 Novel adenosine A3 receptor agonists ADORA3, ADORA2A, ADORA1 L3MBTL1 3590/4885KMT2A 3314/4885MEN1 4611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.