Fluoride Ion

Fluoride Ion

SCHEMBL4075135

COc1ccc(C[n+]2ccc(C#N)cc2)cc1.[F-].[F-].[F-].[F-].[F-].[F-].[Sb+3]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.54
MAOA P21397 1/20 0.54
CHKA P35790 2/20 0.43
CYP2A6 P11509 1/20 0.42
CYP19A1 P11511 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDR P35968 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
F2 P00734 1/20 0.39
PRSS1 P07477 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
VNN1 O95497 1/20 0.39
SNCA P37840 1/20 0.38
IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL4461520 0.97 MAOB (0.54) MAOBMAOACHKACYP2A6CYP19A1
SCHEMBL9871410 0.97 MAOB (0.56) MAOBMAOACHKACYP2A6CYP19A1
Fluoride Ion SCHEMBL4075178 0.78 CHKA (0.49) MAOBMAOACHKAMEN1KMT2A
SCHEMBL7837346 0.78 CHKA (0.49) MAOBCHKAIDO1
Fluoride Ion SCHEMBL125569 0.76 CHKA (0.68) CHKA
SCHEMBL9249583 0.76 TSHR (0.45) MAOBMAOACHKAPOLBMAPT
Fluoride Ion SCHEMBL4075175 0.75 CHKA (0.49) MAOBMAOACHKAMEN1KMT2A
SCHEMBL20053881 0.74 MAOB (0.65) MAOBMAOACYP2A6CYP19A1POLB
SCHEMBL4356760 0.74 CHKA (0.52) MAOBMAOACHKACYP2A6MEN1
SCHEMBL7316077 0.74 MAOB (0.65) MAOBMAOACYP2A6CYP19A1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791824-B1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO KK (JP) 2009-08-05 EP disclosed
US-20090192279-A1 Radically Polymerizable Sulfur-Containing Compound and Radically Polymerizable Sulfur-Containing Polymer SHOWA DENKO K.K. (JP) 2009-07-30 US disclosed
US-7518001-B2 Radically polymerizable sulfur-containing compound and radically polymerizable sulfur-containing polymer SHOWA DENKO K.K. (JP) 2009-04-14 US disclosed
US-20070208149-A1 Radically Polymerizable Sulfur-Containing Compound And Radically Polymerizable Sulfur-Containing Polymer SHOWA DENKO K.K. (JP) 2007-09-06 US disclosed
EP-1791824-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER Showa Denko K.K. (JP) 2007-06-06 EP disclosed
WO-2006033438-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO K.K. (JP) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208149-A1 Radically Polymerizable Sulfur-Containing Compound And Radically Polymerizable Sulfur-Containing Polymer CBS, TST, MSRB3 MAOB 4541/4885MAOA 4205/4885CHKA 2923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.