Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | DRD3 | P35462 | 8/20 | 0.47 |
| ▸ | HTR2A | P28223 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088893 | 0.80 | DRD2 (0.51) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL4084678 | 0.78 | DRD2 (0.57) | DRD2DRD3HTR1AMEN1KMT2A | |
| SCHEMBL4072349 | 0.73 | MEN1 (0.72) | MEN1KMT2AKDM4EPKMSMN1; SMN2 | |
| SCHEMBL4079207 | 0.72 | DRD2 (0.64) | DRD2DRD3HTR2AHTR1AMEN1 | |
| SCHEMBL4081134 | 0.71 | DRD2 (0.59) | DRD2DRD3HTR2AHTR1ASMN1; SMN2 | |
| SCHEMBL4081131 | 0.71 | DRD2 (0.59) | DRD2DRD3HTR2AHTR1ASMN1; SMN2 | |
| SCHEMBL11815786 | 0.71 | MEN1 (0.54) | MEN1KMT2AKDM4EPKMSMN1; SMN2 | |
| SCHEMBL4219110 | 0.70 | MEN1 (0.51) | MEN1KMT2APKMSMN1; SMN2GAA | |
| SCHEMBL4075532 | 0.70 | DRD2 (0.54) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL4087022 | 0.69 | HTR1A (0.49) | DRD2DRD3HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |