Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.64 |
| ▸ | HTR2A | P28223 | 9/20 | 0.64 |
| ▸ | DRD3 | P35462 | 9/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075504 | 0.90 | HTR7 (0.65) | DRD2HTR2ADRD3HTR1AMAPT | |
| SCHEMBL4075434 | 0.83 | DRD2 (0.56) | DRD2HTR2ADRD3HTR1ALMNA | |
| SCHEMBL4083822 | 0.80 | HTR2A (0.61) | DRD2HTR2ADRD3HTR1A | |
| SCHEMBL4081134 | 0.78 | DRD2 (0.59) | DRD2HTR2ADRD3HTR1ALMNA | |
| SCHEMBL4081131 | 0.78 | DRD2 (0.59) | DRD2HTR2ADRD3HTR1ALMNA | |
| SCHEMBL27904395 | 0.78 | HTR1A (1.00) | DRD2HTR2ADRD3HTR1A | |
| SCHEMBL4075532 | 0.78 | DRD2 (0.54) | DRD2HTR2ADRD3HTR1AHTR7 | |
| SCHEMBL4088191 | 0.76 | DRD2 (0.57) | DRD2HTR2ADRD3HTR1ALMNA | |
| SCHEMBL12478625 | 0.76 | DRD2 (1.00) | DRD2HTR2ADRD3 | |
| SCHEMBL13629929 | 0.76 | DRD2 (0.55) | DRD2HTR2ADRD3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |