Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.58 |
| ▸ | ITGAV | P06756 | 20/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 19/20 | 0.58 |
| ▸ | ITGA5 | P08648 | 19/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065491 | 0.87 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4075416 | 0.82 | ITGB1 (0.81) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4067570 | 0.80 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL14104055 | 0.80 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA5 | |
| Hydrochloric Acid SCHEMBL4193237 | 0.79 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4739844 | 0.77 | ITGB3 (0.70) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4065099 | 0.76 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4070703 | 0.74 | ITGB1 (0.85) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4073709 | 0.74 | ITGB1 (0.90) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4065677 | 0.73 | ITGB1 (1.00) | ITGB3ITGAVITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049490-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL]-L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | Astra Zeneca AB (SE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007141473-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL] -L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | ASTRAZENECA AB (SE) | 2007-12-13 | — | — | WO | disclosed |