SCHEMBL4075491

SCHEMBL4075491

CO[SiH](OC)c1ccccc1CI

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
IDO1 P14902 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274033 0.81 GABRA1 (0.38) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL4081156 0.80 MAPT (0.31) MAPT
SCHEMBL22551425 0.79 IDO1 (0.40) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL1263395 0.79 ALDH1A1 (0.32) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL1262921 0.79 ALDH1A1 (0.34) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL29112998 0.79 ALDH1A1 (0.36) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL4078015 0.79
SCHEMBL3482132 0.78 ADRA2A (0.34) ALDH1A1GAAMAPTTAAR1
SCHEMBL9148449 0.77 CA1 (0.38) ALDH1A1MAPT
SCHEMBL6114627 0.76 GABRA1 (0.44) ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed