Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298089 | 1.00 | FTO (0.48) | FTONPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8965768 | 0.90 | NPC1 (0.46) | FTONPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8999319 | 0.90 | NPC1 (0.46) | FTONPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4070857 | 0.81 | POLB (0.55) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8971101 | 0.80 | MEN1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8999418 | 0.80 | MEN1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8965380 | 0.77 | NPC1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8965378 | 0.77 | NPC1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL12126424 | 0.73 | RPS6KA3 (0.48) | NPC1RAB9AMAPTTDP1LMNA | |
| SCHEMBL23401483 | 0.73 | NPC1 (0.59) | NPC1RAB9AMAPTSMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8790544-B2 | Liquid-crystalline coating solution and polarizing film | NITTO DENKO CORPORATION (JP) | 2014-07-29 | — | — | US | disclosed |
| US-20120105795-A1 | LIQUID-CRYSTALLINE COATING SOLUTION AND POLARIZING FILM | NITTO DENKO CORPORATION (JP) | 2012-05-03 | — | — | US | disclosed |