⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983204 | 1.00 | BRD4 (0.41) | — | |
| Cyclohexane SCHEMBL27414669 | 0.93 | LMNA (0.42) | — | |
| SCHEMBL28561589 | 0.89 | BRD4 (0.35) | — | |
| SCHEMBL28086415 | 0.82 | BRD4 (0.31) | — | |
| SCHEMBL28555227 | 0.78 | GPR84 (0.43) | — | |
| SCHEMBL21917363 | 0.76 | — | — | |
| SCHEMBL297038 | 0.76 | — | — | |
| SCHEMBL9443405 | 0.74 | CRBN (0.35) | — | |
| SCHEMBL4348692 | 0.73 | ADRA1D (0.37) | — | |
| SCHEMBL9118472 | 0.72 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5997 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099316-A1 | COMPOUNDS AND METHODS FOR REDUCING ARHGEF6 EXPRESSION | ASTRAZENECA AB (SE) | 2026-05-15 | — | — | WO | claimed |
| US-20260109977-A1 | MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION | TRILINK BIOTECHNOLOGIES, LLC (US) | 2026-04-23 | — | — | US | claimed |
| EP-4617375-A2 | METHODS, COMPOSITIONS AND SYSTEMS FOR IMPROVING THE BINDING OF METHYLATED POLYNUCLEOTIDES | Guardant Health, Inc. (US) | 2025-09-17 | — | — | EP | claimed |
| CN-120054582-A | Mono-atom catalyst for denitration and sulfur resistance and preparation method thereof | 福州大学 | 2025-05-30 | — | — | CN | claimed |
| EP-4065725-B1 | METHODS, COMPOSITIONS AND SYSTEMS FOR IMPROVING THE BINDING OF METHYLATED POLYNUCLEOTIDES | GUARDANT HEALTH INC (US) | 2025-05-21 | — | — | EP | claimed |
| US-12281138-B2 | 5′-cap-trinucleotide- or higher oligonucleotide compounds and their use in stabilizing RNA, expressing proteins in therapy | BIONTECH RNA PHARMACEUTICALS GMBH (DE) | 2025-04-22 | — | — | US | claimed |
| WO-2025068896-A1 | COMPOUNDS AND METHODS FOR REDUCING PSD3 EXPRESSION | ASTRAZENECA AB (SE) | 2025-04-03 | — | — | WO | claimed |
| US-20250066828-A1 | C-NUCLEOSIDE MONOPHOSPHATE SYNTHESIS | ENGINZYME AB (SE) | 2025-02-27 | — | — | US | claimed |
| EP-4463560-A1 | C-NUCLEOSIDE MONOPHOSPHATE SYNTHESIS | Uab Biomatter Designs (LT) | 2024-11-20 | — | — | EP | claimed |
| CN-118772068-A | Preparation method of deuterated methyl uric acid standard substance | 上海原思标物科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-1236315-A | A pharmaceutical composition containing kynurenine and thymine or tryptophan and thymine | PAUL HUBER (BR) | 1999-11-24 | — | — | CN | claimed |
| CN-1043769-C | L-nucleosides for treating hepatitis B virus and Epstein-Barr virus and uses thereof | UNIV GEORGIA (US) | 1999-06-23 | — | — | CN | claimed |
| US-5891684-A | RIBOZYMES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | claimed |
| EP-0799313-A2 | METHOD AND REAGENT FOR TREATMENT OF ARTHRITIC CONDITIONS, INDUCTION OF GRAFT TOLERANCE AND REVERSAL OF IMMUNE RESPONSES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1997-10-08 | — | — | EP | claimed |
| US-5672501-A | Base-modified enzymatic nucleic acid | RIBOZYME PHARMACEUTICALS, INC. (US) | 1997-09-30 | — | — | US | claimed |
| CN-1143966-A | L-nucleosides for the treatment of hepatitis B virus and Epstein-Barr virus | UNIV GEORGIA (US) | 1997-02-26 | — | — | CN | claimed |
| WO-1996018736-A2 | METHOD AND REAGENT FOR TREATMENT OF ARTHRITIC CONDITIONS, INDUCTION OF GRAFT TOLERANCE AND REVERSAL OF IMMUNE RESPONSES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1996-06-20 | — | — | WO | claimed |
| CN-1013076-B | PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 1991-07-10 | — | — | CN | claimed |
| CN-86101792-A | The preparation method of heterogeneous ring compound | — | 1986-11-12 | — | — | CN | claimed |
| WO-1983002891-A1 | URACIL DERIVATIVES AS ANTI-SEBORRHEIC ADDITIVES FOR COSMETIC PRODUCTS | Möller, Hinrich | 1983-09-01 | — | — | WO | claimed |