Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074344 | 0.81 | CCR1 (0.47) | CCR1ALDH1A1LMNAMAPT | |
| SCHEMBL2353510 | 0.80 | ALDH1A1 (0.47) | CCR1ALDH1A1LMNAMAPT | |
| SCHEMBL27642379 | 0.77 | CCR1 (0.47) | CCR1ALDH1A1LMNAMAPT | |
| SCHEMBL3817807 | 0.76 | CCR1 (0.44) | CCR1ALDH1A1LMNAMAPT | |
| SCHEMBL3225431 | 0.76 | CCR1 (0.52) | CCR1MAPT | |
| SCHEMBL3811823 | 0.76 | ALDH1A1 (0.44) | CCR1ALDH1A1LMNAMAPT | |
| SCHEMBL3221137 | 0.76 | LGMN (0.61) | ALDH1A1LMNAMAPT | |
| SCHEMBL3215648 | 0.75 | NOTUM (0.59) | CCR1 | |
| SCHEMBL30755065 | 0.75 | NOTUM (0.59) | CCR1 | |
| SCHEMBL4071812 | 0.75 | CCR1 (0.49) | CCR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084146-A1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Brystol-Myers Squibb Company (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008042925-A1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-10 | — | — | WO | disclosed |