SCHEMBL407624

SCHEMBL407624

CCOC(COCCC(=O)O)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
PLA2G4B P0C869 1/20 0.33
ALDH1A1 P00352 3/20 0.32
AKR1B1 P15121 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GPR84 Q9NQS5 7/20 0.31
PPARG P37231 7/20 0.31
PPARD Q03181 7/20 0.31
PPARA Q07869 7/20 0.31
HDAC11 Q96DB2 5/20 0.31
TSHR P16473 4/20 0.31
PTPN1 P18031 3/20 0.31
TLR2 O60603 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
FABP4 P15090 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167185 0.78 FFAR3 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL8986187 0.77 ALDH1A1 (0.34) ALDH1A1EGLN1
SCHEMBL27523 0.75
SCHEMBL8665800 0.75 ALDH1A1 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL18349784 0.75 THRB (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL8845942 0.74 AKR1B1 (0.42) PLA2G4BALDH1A1AKR1B1GPR84PPARG
SCHEMBL27820166 0.74 EGLN1 (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL8932043 0.74 ALDH1A1 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL439265 0.74 ALDH1A1 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL9883735 0.74 ALDH1A1 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120022234-A1 METHOD FOR THE PURIFICATION OF ALBUMIN CONJUGATES BOUSQUET-GAGNON NATHALIE (CA) 2012-01-26 US disclosed
EP-2230257-A1 Method for the purification of albumin conjugates ConjuChem Biotechnologies Inc. (CA) 2010-09-22 EP disclosed
EP-2100904-B1 Solid phase for use in a method for the purification of albumin conjugates CONJUCHEM BIOTECHNOLOGIES INC (CA) 2010-07-07 EP disclosed
EP-2100904-A1 Solid phase for use in a method for the purification of albumin conjugates ConjuChem Biotechnologies Inc. (CA) 2009-09-16 EP disclosed
EP-1745078-B1 METHOD FOR THE PURIFICATION OF ALBUMIN CONJUGATES CONJUCHEM BIOTECHNOLOGIES INC (CA) 2009-06-17 EP disclosed
US-20080146783-A1 Method for the purification of albumin conjugates CONJUCHEM BIOTECHNOLOGIES INC. 2008-06-19 US disclosed
US-7307148-B2 Method for purification of albumin conjugates CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2007-12-11 US disclosed
EP-1745078-A4 METHOD FOR THE PURIFICATION OF ALBUMIN CONJUGATES CONJUCHEM BIOTECHNOLOGIES INC (CA) 2007-08-01 EP disclosed
EP-1745078-A1 METHOD FOR THE PURIFICATION OF ALBUMIN CONJUGATES ConjuChem Biotechnologies Inc. (CA) 2007-01-24 EP disclosed
US-20050267293-A1 Method for purification of albumin conjugates CONJUCHEM, INC. (CA) 2005-12-01 US disclosed
WO-2005103087-A1 METHOD FOR THE PURIFICATION OF ALBUMIN CONJUGATES CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2005-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022234-A1 METHOD FOR THE PURIFICATION OF ALBUMIN CONJUGATES ALB, DNPEP, SLC7A1 FFAR3 2696/4885HDAC3 3181/4885HDAC1 3082/4885
US-20050267293-A1 Method for purification of albumin conjugates ALB, DNPEP, SLC7A1 FFAR3 2973/4885HDAC3 3478/4885HDAC1 3225/4885
US-20080146783-A1 Method for the purification of albumin conjugates ALB, DNPEP, SLC7A1 FFAR3 2696/4885HDAC3 3181/4885HDAC1 3082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.